bioinformatics
371
ncbi-gene-retrieval
Retrieve gene information from NCBI Gene database by gene IDs to obtain genomic details, function, and expression data.
SpectrAI-Initiative
research
sorting
stars
current ordering strategy
query
all entries
refine the visible subset
bioinformatics
371
rare-disease-genetics
Rare Disease Genetic Analysis - Analyze rare disease genetics: Monarch phenotype-disease mapping, ClinVar variants, NCBI gene data, and OpenTargets. Use this skill for rare disease genetics tasks involving get HPO ID by phenotype get joint associated diseases by HPO ID list clinvar search get associated targets by disease efoId. Combines 4 tools from 3 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
pharmacogenomics-analysis
Pharmacogenomics Analysis - Pharmacogenomics analysis: FDA pharmacogenomics info, variant effects, ClinVar pathogenicity, and gene expression. Use this skill for pharmacogenomics tasks involving get pharmacogenomics info by drug name get vep hgvs clinvar search get gene expression across cancers. Combines 4 tools from 4 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
polypharmacology-analysis
Polypharmacology Analysis - Analyze a drug's multi-target pharmacology: get targets from ChEMBL, functional enrichment from STRING, and pathway links from KEGG. Use this skill for pharmacology tasks involving get target by name get functional enrichment kegg link get mechanism by id. Combines 4 tools from 3 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
protein-database-crossref
Protein Cross-Database Reference - Cross-reference protein: UniProt entry, NCBI gene, Ensembl xrefs, and PDB structure search. Use this skill for proteomics tasks involving get uniprotkb entry by accession get gene metadata by gene name get xrefs symbol retrieve protein data by pdbcode. Combines 4 tools from 4 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
tcga-gene-expression
Retrieve gene expression data from TCGA (The Cancer Genome Atlas) to analyze cancer-specific expression patterns.
SpectrAI-Initiative
research
bioinformatics
371
population-genetics
Population Genetics Analysis - Analyze population genetics: Ensembl variation populations, linkage disequilibrium, and variant frequency data. Use this skill for population genetics tasks involving get info variation populations get ld get variation get variant recoder. Combines 4 tools from 1 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
disease-drug-landscape
Disease-Drug Landscape Analysis - Map the drug landscape for a disease: OpenTargets disease drugs, FDA indications, and clinical studies. Use this skill for drug discovery tasks involving get associated drugs by target name get drug names by indication get clinical studies info by drug name. Combines 3 tools from 2 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
cell-line-assay-analysis
Cell Line Assay Analysis - Analyze cell line assays: ChEMBL cell line info, assay search, activity data, and target info. Use this skill for cell biology tasks involving get cell line by id search assay search activity get target by name. Combines 4 tools from 1 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
structural-pharmacogenomics
Structural Pharmacogenomics - Link structure to pharmacogenomics: variant effect, protein structure change, drug binding, and clinical data. Use this skill for pharmacogenomics tasks involving get vep hgvs pred protein structure esmfold boltz binding affinity get pharmacogenomics info by drug name. Combines 4 tools from 3 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
structural-homology-modeling
Structural Homology & Evolution Analysis - Analyze protein evolution: get gene tree from Ensembl, find homologs, compare sequences, and predict structure. Use this skill for evolutionary biology tasks involving get homology symbol get genetree member symbol calculate protein sequence properties pred protein structure esmfold. Combines 4 tools from 3 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
regulatory-region-analysis
Regulatory Region Analysis - Analyze regulatory regions: get overlapping features, binding matrix, sequence, and phenotype associations. Use this skill for epigenomics tasks involving get overlap region get species binding matrix get sequence get phenotype region. Combines 4 tools from 2 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
snp-functional-analysis
SNP Functional Impact Analysis - Analyze SNP function: VEP prediction, variation details, phenotype association, and literature evidence. Use this skill for functional genomics tasks involving get vep id get variation get phenotype accession pubmed search. Combines 4 tools from 2 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
string-ppi-enrichment
Analyze protein-protein interaction enrichment using STRING database to identify functional networks and pathway associations.
SpectrAI-Initiative
research
bioinformatics
371
protein-structure-analysis
Protein Structure Comprehensive Analysis - Comprehensive structure analysis: download PDB, extract chains, calculate geometry, quality metrics, and composition. Use this skill for structural biology tasks involving retrieve protein data by pdbcode extract pdb chains calculate pdb structural geometry calculate pdb quality metrics calculate pdb composition info. Combines 5 tools from 1 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
synthetic-biology-design
Synthetic Biology Design - Design synthetic biology construct: gene lookup, codon optimization, protein property prediction, and structure prediction. Use this skill for synthetic biology tasks involving get sequence id DegenerateCodonCalculatorbyAminoAcid calculate protein sequence properties pred protein structure esmfold. Combines 4 tools from 4 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
protein-interaction-network
Protein Interaction Network Analysis - Build protein interaction network: map identifiers with STRING, get PPI network, compute enrichment, and link to KEGG pathways. Use this skill for systems biology tasks involving mapping identifiers get string network interaction get ppi enrichment kegg link. Combines 4 tools from 2 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
protein-blast-search
Search for similar protein sequences in UniProt Swiss-Prot database using BLAST to identify homologous proteins and functional relationships.
SpectrAI-Initiative
research
bioinformatics
371
protein-classification-analysis
Protein Classification Analysis - Classify protein: ChEMBL protein classification, UniProt entry, InterPro domains, and Ensembl biotypes. Use this skill for protein science tasks involving search protein classification get uniprotkb entry by accession query interpro get info biotypes. Combines 4 tools from 4 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
protein-complex-analysis
Protein Complex Visualization & Analysis - Analyze protein complex: download structure, visualize complex, extract chains, and calculate quality metrics. Use this skill for structural biology tasks involving retrieve protein data by pdbcode visualize complex extract pdb chains calculate pdb basic info. Combines 4 tools from 1 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
chromosome-analysis
Chromosome Structure Analysis - Analyze chromosome: NCBI summary, UCSC cytoband, genome sequence, and Ensembl assembly info. Use this skill for cytogenetics tasks involving get chromosome summary get cytoband get chromosome sequence get info assembly. Combines 4 tools from 3 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
disease-protein-profiling
Disease Protein Profiling - Profile a disease protein: UniProt data, AlphaFold structure, InterPro domains, phenotype associations from Ensembl. Use this skill for medical proteomics tasks involving query uniprot download alphafold structure query interpro get phenotype gene. Combines 4 tools from 2 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
systems-pharmacology
Systems Pharmacology Analysis - Systems pharmacology: drug targets, protein interactions, pathway enrichment, and gene expression. Use this skill for systems pharmacology tasks involving get target by name get string network interaction get functional enrichment get gene expression across cancers. Combines 4 tools from 3 SCP server(s).
SpectrAI-Initiative
research
bioinformatics
371
drugsda-esmfold
Use ESMFold model to predict 3D structure of the input protein sequence.
SpectrAI-Initiative
research