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Research

Scientific computing and academic tools.

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bioinformatics
124

biopython-phylo

Use Bio.Phylo to read/write phylogenetic trees and perform visualization and statistics; use when tree parsing/conversion, pruning/rerooting, distance calculation, or plotting is required.

aipoch
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bioinformatics
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biopython-advanced

Advanced Biopython modules for motifs, population genetics, sequence utilities, restriction analysis, clustering, and GenomeDiagram visualization; use when you need extended bioinformatics analysis beyond basic sequence I/O and alignment.

aipoch
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bioinformatics
124

anndata

Data structure for annotated matrices in single-cell analysis; use when reading/writing .h5ad (or zarr) and exchanging data with the scverse ecosystem.

aipoch
aipoch
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bioinformatics
124

dual-disease-transcriptomic-ml-planner

Generates complete dual-disease transcriptomic + machine learning research designs from a user-provided disease pair. Use when users want to identify shared DEGs, common hub genes, cross-disease biomarkers, or shared molecular mechanisms between two diseases using public GEO data. Triggers: "shared biomarker study for two diseases", "dual-disease transcriptomic ML paper", "identify common DEGs between disease A and B", "cross-disease hub gene discovery", "shared DEG + PPI + ROC design", "immune infiltration shared biomarker", or "I want to study disease X and Y together". Always outputs four workload configurations (Lite / Standard / Advanced / Publication+) with a recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, and publication upgrade path.

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bioinformatics
124

biodbnet-api

Access bioDBnet REST services for biological identifier conversion, pathway retrieval, and ortholog mapping. Use when you need to convert gene/protein IDs, find pathways, or retrieve biological annotations via bioDBnet.

aipoch
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bioinformatics
124

variant-annotation

Query and annotate gene variants from ClinVar and dbSNP databases. \n\.

aipoch
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bioinformatics
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string-database

Access the STRING database to map identifiers, retrieve protein–protein interaction networks, and run functional/PPI enrichment when you need interaction context for a gene/protein set.

aipoch
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bioinformatics
124

patent-landscape

Use when analyzing biotech patent landscapes, identifying white spaces in pharmaceutical IP, tracking competitor patents, or assessing freedom to operate for drug development. Provides comprehensive patent analysis and strategic insights for life sciences innovation.

aipoch
aipoch
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bioinformatics
124

hgnc-api

Access the HGNC (HUGO Gene Nomenclature Committee) database to search for and retrieve gene information including symbols, names, IDs, and other metadata.

aipoch
aipoch
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bioinformatics
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gget

Unified CLI/Python interface for querying genomic, proteomic, structure, and expression data across 20+ bioinformatics databases; use when you need fast, scriptable retrieval by gene/protein IDs or keywords.

aipoch
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bioinformatics
124

gwas-database

Query the NHGRI-EBI GWAS Catalog to retrieve SNP–trait associations, study metadata, and (when available) summary statistics when you need evidence for a variant, trait/disease, gene, or genomic region.

aipoch
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bioinformatics
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gene-database

Query the NCBI Gene database via E-utilities and the NCBI Datasets API; use it when you need to search genes by symbol/ID and retrieve annotations (RefSeq, GO, location, phenotype) for single or batch gene lists.

aipoch
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bioinformatics
124

ensembl-database

Access Ensembl REST API for vertebrate genomic data; use when you need gene/ID lookups, sequence retrieval, variant effect prediction (VEP), or homology/assembly coordinate mapping.

aipoch
aipoch
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bioinformatics
124

encori-api

Access ENCORI (StarBase) database for miRNA-target, RNA-RNA, and other regulatory data. Invoke when user asks to search ENCORI or retrieve regulatory interactions.

aipoch
aipoch
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bioinformatics
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ena-database

Access the European Nucleotide Archive (ENA) via REST APIs and FTP/Aspera to search and retrieve sequences, raw reads (FASTQ), assemblies, and metadata when you have accession IDs or need metadata-driven discovery for genomics pipelines.

aipoch
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bioinformatics
124

bio-ontology-mapper

Map unstructured biomedical text to standardized ontologies (SNOMED CT.

aipoch
aipoch
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bioinformatics
124

neuropixels-analysis

End-to-end Neuropixels extracellular electrophysiology analysis (SpikeGLX/Open Ephys/NWB) including preprocessing, motion correction, Kilosort4 spike sorting, QC metrics, and Allen/IBL-style curation; use when processing Neuropixels recordings or when users mention Neuropixels, SpikeGLX, Open Ephys, Kilosort, quality metrics, drift/motion correction, or unit curation.

aipoch
aipoch
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bioinformatics
124

neoantigen-predictor

Predict neoantigens that may be recognized by the immune system based.

aipoch
aipoch
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bioinformatics
124

motif-logo-generator

Generate publication-quality sequence logos for DNA or protein motifs.

aipoch
aipoch
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bioinformatics
124

sequence-alignment

A skill for performing sequence alignment using NCBI BLAST API. Supports nucleotide and protein sequence comparison against major biological databases.

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aipoch
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