cosmic-database
Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology. Requires authentication.
Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology. Requires authentication.
Framework for computational fluid dynamics simulations using Python. Use when running fluid dynamics simulations including Navier-Stokes equations (2D/3D), shallow water equations, stratified flows, or when analyzing turbulence, vortex dynamics, or geophysical flows. Provides pseudospectral methods with FFT, HPC support, and comprehensive output analysis.
Comprehensive biosignal processing toolkit for analyzing physiological data including ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use this skill when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements. Applicable for heart rate variability analysis, event-related potentials, complexity measures, autonomic nervous system assessment, psychophysiology research, and multi-modal physiological signal integration.
Search 78 public scientific, biomedical, materials science, and economic databases via their REST APIs and return structured JSON results. Covers physics/astronomy (NASA, NIST, SDSS, SIMBAD, Exoplanet Archive), earth/environment (USGS, NOAA, EPA, OpenWeatherMap), chemistry/drugs (PubChem, ChEMBL, DrugBank, FDA, KEGG, DailyMed, ZINC, BindingDB), materials science (Materials Project, COD), biology/genomics (Reactome, BRENDA, UniProt, STRING, Ensembl, NCBI Gene, GEO, GTEx, PDB, AlphaFold, InterPro, ChEBI, BioGRID, Gene Ontology, QuickGO, NCBI Protein/Taxonomy, dbSNP, SRA, ENA, gnomAD, UCSC Genome, ENCODE, JASPAR, MouseMine, PRIDE, LINCS L1000, Human Protein Atlas, Human Cell Atlas, RummaGEO, Metabolomics Workbench, EMDB, Addgene), disease/clinical (COSMIC, Open Targets, ClinPGx, ClinicalTrials.gov, OMIM, ClinVar, GDC/TCGA, cBioPortal, DisGeNET, GWAS Catalog, Monarch, HPO), regulatory (FDA, USPTO, SEC EDGAR), economics/finance (FRED, BEA, BLS, Federal Reserve, World Bank, ECB, US Treasury, Alpha Vantage, Data Com
This skill should be used when the user asks to "summarize videos", "summarize podcasts", "research a topic using media", "bulk summarize content", "scan YouTube channels", "scan podcast feeds", "create podcast notes", "digest conference talks", "summarize Apple Podcasts", or mentions video/podcast research, media summarization, or bulk content processing.
Measure quality effectively with actionable metrics. Use when establishing quality dashboards, defining KPIs, or evaluating test effectiveness.
Multi-model AI consultation and research. Supports CONSULTATION MODE (ask single expert), RESEARCH MODE (parallel multi-agent), or DELIBERATION MODE (agents debate and refine). USE WHEN user says 'ask gemini', 'consult codex' (consultation), 'do research' (research), or 'deliberate on' (deliberation).
Move testing activities earlier in the development lifecycle to catch defects when they're cheapest to fix. Use when implementing TDD, CI/CD, or early quality practices.
Testing in production with feature flags, canary deployments, synthetic monitoring, and chaos engineering. Use when implementing production observability or progressive delivery.
Parse HEC-RAS compute output from HDF files to extract execution status, diagnostic messages, and performance metrics. Converts raw computation messages into structured diagnostics for workflow orchestration. Use when checking plan completion status, extracting compute messages, diagnosing execution failures, analyzing runtime performance, or interpreting HEC-RAS error codes. Keywords: compute messages, execution status, plan complete, runtime, performance, error diagnostics, HEC-RAS output, simulation results, warnings, convergence, instability, time step, iteration.
Advanced exploratory testing techniques with Session-Based Test Management (SBTM), RST heuristics, and test tours. Use when planning exploration sessions, investigating bugs, or discovering unknown quality risks.
Epistemological tracking system for managing facts, conclusions, and provenance chains with Git integrity and semantic search. Integrates with Quarto for visual provenance analysis. Use when analyzing data from multiple sources, conducting research, working with metrics/surveys, making data-driven conclusions, or tracking complex findings. Triggers on data analysis (analyze data, metrics, survey, research, findings, insights), conclusions (conclude, recommend, decide, infer), quantitative work (percentage, trend, correlation, statistic), source attribution (according to, based on, from source), or any epistemological tracking. Skip for trivial calculations.
Use when the user asks about current weather, forecasts, historical weather, air quality, marine conditions, flooding, or elevation for any location worldwide.
Run qmd health check for this project. Triggers on "qmd doctor", "check qmd health", "qmd problems", "diagnose qmd".
Expert YARA rule authoring, review, and optimization. Use when writing new YARA rules, reviewing existing rules for quality issues, optimizing rule performance, or converting detection logic to YARA syntax. Covers rule naming conventions, string selection, condition optimization, performance tuning, and automated quality checks based on yaraQA.
Screenshot-obsessed, evidence-based QA specialist that requires visual proof for everything and defaults to finding issues. Adapted from msitarzewski/agency-agents.
Apple HIG guidance for selection and input controls including pickers, toggles, sliders, steppers, segmented controls, combo boxes, text fields, text views, labels, token fields, virtual keyboards, rating indicators, and gauges. Use this skill when the user says "picker or segmented control," "how should my form look," "what keyboard type should I use," "toggle vs checkbox," or asks about picker design, toggle, switch, slider, stepper, text field, text input, segmented control, combo box, label, token field, virtual keyboard, rating indicator, gauge, form design, input validation, or control state management. Cross-references: hig-components-menus, hig-components-dialogs, hig-components-search.
Expert in experiment design, execution tracking, and data-driven decision making for A/B tests, feature experiments, and hypothesis validation. Adapted from msitarzewski/agency-agents.
Comprehensive test result evaluation, quality metrics analysis, defect prediction, and release readiness assessment with statistical rigor. Adapted from msitarzewski/agency-agents.
Capture a resonance moment — when something clicks, sparks joy, or feels right. Logs what resonated, when, why, and how. Use when user says "resonance", "yes!", "cool!", "very cool!", "love it", "that's it!", "exactly!", or expresses strong positive reaction to something just discussed. Do NOT trigger for general praise like "thanks" or "ok".
Unvarnished technical criticism combining Linus Torvalds' precision, Gordon Ramsay's standards, and James Bach's BS-detection. Use when code/tests need harsh reality checks, certification schemes smell fishy, or technical decisions lack rigor. No sugar-coating, just surgical truth about what's broken and why.