Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology. Requires authentication.
Framework for computational fluid dynamics simulations using Python. Use when running fluid dynamics simulations including Navier-Stokes equations (2D/3D), shallow water equations, stratified flows, or when analyzing turbulence, vortex dynamics, or geophysical flows. Provides pseudospectral methods with FFT, HPC support, and comprehensive output analysis.
Use this skill when working with scientific research tools and workflows across bioinformatics, cheminformatics, genomics, structural biology, proteomics, and drug discovery. This skill provides access to 600+ scientific tools including machine learning models, datasets, APIs, and analysis packages. Use when searching for scientific tools, executing computational biology workflows, composing multi-step research pipelines, accessing databases like OpenTargets/PubChem/UniProt/PDB/ChEMBL, performing tool discovery for research tasks, or integrating scientific computational resources into LLM workflows.
Cross-session memory — save insights after research, restore prior context before planning or research. Restore first, compact second.
Data format conventions for datasets and plmodules
Python interface to OpenMS for mass spectrometry data analysis. Use for LC-MS/MS proteomics and metabolomics workflows including file handling (mzML, mzXML, mzTab, FASTA, pepXML, protXML, mzIdentML), signal processing, feature detection, peptide identification, and quantitative analysis. Apply when working with mass spectrometry data, analyzing proteomics experiments, or processing metabolomics datasets.
Comprehensive biosignal processing toolkit for analyzing physiological data including ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use this skill when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements. Applicable for heart rate variability analysis, event-related potentials, complexity measures, autonomic nervous system assessment, psychophysiology research, and multi-modal physiological signal integration.
Access Human Metabolome Database (220K+ metabolites). Search by name/ID/structure, retrieve chemical properties, biomarker data, NMR/MS spectra, pathways, for metabolomics and identification.
Generate professional drug discovery reports including target dossiers, competitive briefs, and Go/No-Go decision summaries. Use this skill when you need formatted reports for presentations, decision meetings, or documentation. Supports multiple output formats. Keywords: report, dossier, decision, go-no-go, brief, presentation
Global drug development pipeline tracking by disease, target, mechanism, or company. Use for competitive intelligence, opportunity identification, and trend analysis. Keywords: pipeline, drug development, clinical trials, R&D tracking, competitive landscape
Use when scanning external trends for strategic planning, monitoring PESTLE forces (Political, Economic, Social, Technological, Legal, Environmental), detecting weak signals (early indicators of change), planning scenarios for multiple futures, setting signposts and indicators for early warning, or when user mentions environmental scanning, horizon scanning, trend analysis, scenario planning, strategic foresight, futures thinking, or emerging issues monitoring.
Use when writing or reviewing career documents including research statements, teaching statements, diversity statements, CVs, or biosketches. Invoke when user mentions research statement, teaching philosophy, diversity statement, biosketch, academic CV, faculty application, or needs help with career narrative, positioning, or professional documents for academic advancement.
Detect potential memory leaks and analyze memory usage patterns in code. Use when troubleshooting performance issues related to memory growth or identifying leak sources. Trigger with phrases like "detect memory leaks", "analyze memory usage", or "find memory issues".
Align architecture and team structure using inverse Conway maneuver
Use when reviewing or editing research manuscripts, journal articles, reviews, or perspectives. Invoke when user mentions manuscript, paper draft, article, research writing, journal submission, reviewer feedback, or needs to improve scientific writing clarity, structure, or argumentation in their manuscript.
Split datasets into training, validation, and testing sets for ML model development. Use when requesting "split dataset", "train-test split", or "data partitioning".
Execute clustering algorithms (K-means, DBSCAN, hierarchical) to identify data groups. Use when requesting "run clustering", "cluster analysis", or "group data points".
Research Python/Z3 patterns and APIs for semantic theory development. Invoke for Python-language research tasks.
Conduct general research using web search, documentation, and codebase exploration. Invoke for non-Lean research tasks.
