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Research

Scientific computing and academic tools.

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scientific-computing
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design-dsrna

Design dsRNA candidates using sliding window algorithm

katalyzeAI
katalyzeAI
research
open
bioinformatics
0

integrate-road-network

Integrate real-world street networks into VRP problems using OpenStreetMap data. Use when loading real map data, creating instances from actual locations, computing network-based distances, or building tutorials with real-world scenarios. Guides through installation, loading areas, extracting nodes, computing distance matrices, and creating PDPTW instances from map data.

dudusoar
dudusoar
research
open
scientific-computing
0

bio-igv

This skill should be used when the user needs to visualize BAM alignment files in IGV (Integrative Genomics Viewer). Triggers include requests to generate IGV screenshots, visualize genomic regions with multiple BAM tracks, or create batch visualizations for WGS analysis results.

dakesan
dakesan
research
open
bioinformatics
0

sparse-expression-visualization

Visualization patterns for sparse single-cell gene expression data. Trigger: boxplots flat at zero, single-cell expression plots, sparse data visualization

smith6jt-cop
smith6jt-cop
research
open
scientific-computing
0

bio-fasta

Read/write FASTA, GenBank, FASTQ files. Sequence manipulation (complement, translate). Indexed random access via faidx. For NGS pipelines (SAM/BAM/VCF), use pysam. For BLAST, use gget or blat-integration.

dakesan
dakesan
research
open
scientific-computing
0

envi-pkg-local-improved

ENVI spatial transcriptomics analysis toolkit - comprehensive documentation with tutorials and Python source code

Ketomihine
Ketomihine
research
open
bioinformatics
0

scanpy-complete

Scanpy 单细胞分析工具包 - 100%覆盖文档(API+教程+预处理+分析+可视化)

Ketomihine
Ketomihine
research
open
bioinformatics
0

archr-local

ArchR docs served from downloaded_docs/archr_scrape - comprehensive scATAC-seq analysis toolkit with all HTML files explicitly listed

Ketomihine
Ketomihine
research
open
scientific-computing
0

ligandmpnn-reference

LigandMPNN sequence design reference. Use when working with LigandMPNN, ProteinMPNN, sequence design, amino acid biasing, fixed residues, temperature, side chain packing, or membrane protein design.

polaires
polaires
research
open
scientific-computing
0

alphafold-database

Access AlphaFold 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and structural biology.

Sologa
Sologa
research
open
bioinformatics
0

mip-research

Phase 1 of MIP pipeline - Research Gatsby metaphor scholarship, establish seed CMT systems, and document MIP procedure for annotators.

gjohnsx
gjohnsx
research
open
bioinformatics
0

trial-sequential-analysis

Teach Trial Sequential Analysis (TSA) for controlling type I and II errors in cumulative meta-analyses. Use when users need to assess if meta-analysis has sufficient information, want to avoid premature conclusions, or need to plan future trials.

matheus-rech
matheus-rech
research
open
scientific-computing
0

bio-blast

NCBI BLAST sequence similarity search using BioPython. Use when a user wants to run BLAST programmatically with blastn/blastp and retrieve results in JSON format.

dakesan
dakesan
research
open
bioinformatics
0

segmentation

Isolates skin regions from background clutter using calibrated thresholds for downstream analysis

do-ops885
do-ops885
research
open
bioinformatics
0

context-map

Fast repository indexing for RLM workflows. Use before analysis to reduce context drift.

oornnery
oornnery
research
open
scientific-computing
0

lammps-simulation

Run LAMMPS molecular dynamics simulations. Use when asked to run MD simulations, energy minimization, equilibration, production runs, or calculate properties like diffusion, RDF, MSD. Supports both CPU and GPU execution.

fl-sean03
fl-sean03
research
open
scientific-computing
0

bio-cosmic

This skill should be used when the user needs to query COSMIC Cancer Gene Census to check if genes are known cancer genes. Triggers include requests to annotate genes with cancer information, check if variants are in cancer genes, or retrieve cancer gene properties from COSMIC database.

dakesan
dakesan
research
open
bioinformatics
0

ml-integration-patterns

Machine learning integration patterns for rRNA-Phylo covering three use cases - rRNA sequence classification (supervised learning with sklearn/PyTorch), multi-tree consensus (ensemble methods), and generative tree synthesis (GNNs/transformers). Includes feature engineering, model training, hyperparameter tuning, model serving, versioning, and evaluation metrics for bioinformatics ML workflows.

roeimed0
roeimed0
research
open
bioinformatics
0

time-to-event-methods

Survival analysis methods including weighted logrank, MaxCombo, RMST, and milestone tests. Use when analyzing TTE data or choosing analysis methods for non-proportional hazards.

choxos
choxos
research
open
bioinformatics
0

meta-analysis

Complete meta-analysis generation for neurosurgical outcomes

matheus-rech
matheus-rech
research
open
scientific-computing
0

tidy-itc-workflow

Master tidy modelling patterns for ITC analyses following TMwR principles. Covers workflow structure, consistent interfaces, reproducibility best practices, and data validation. Use when setting up ITC analysis projects or building pipelines.

choxos
choxos
research
open
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