home/categories/bioinformatics/gptomics-bioskills-causal-genomics-mendelian-randomization-skill-md
bioinformaticsresearch

bio-causal-genomics-mendelian-randomization

Estimate causal effects between exposures and outcomes using genetic variants as instrumental variables with TwoSampleMR. Implements IVW, MR-Egger, weighted median, and MR-PRESSO methods for robust causal inference from GWAS summary statistics. Use when testing whether an exposure causally affects an outcome using genetic instruments.

GPTomics
maintainer
GPTomics
آخر تحديث 4/6/2026
النجوم
471
التفرعات
81
quick start

Installation and usage

Estimate causal effects between exposures and outcomes using genetic variants as instrumental variables with TwoSampleMR. Implements IVW, MR-Egger, weighted median, and MR-PRESSO methods for robust causal inference from GWAS summary statistics. Use when testing whether an exposure causally affects an outcome using genetic instruments.

التثبيت
$ install --globalskills.sh
الاستخدام

بعد التثبيت، يمكنك استخدام هذه المهارة بتشغيل الأمر التالي في الطرفية:

skills use bio-causal-genomics-mendelian-randomization