home/categories/bioinformatics/gptomics-bioskills-gene-regulatory-networks-multiomics-grn-skill-md
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bio-gene-regulatory-networks-multiomics-grn

Build enhancer-driven gene regulatory networks by integrating single-cell RNA-seq and ATAC-seq data using SCENIC+ to identify eRegulons linking transcription factors to enhancers and target genes. Use when analyzing 10x multiome or paired scRNA+scATAC data to infer cis-regulatory GRNs.

GPTomics
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GPTomics
Updated 2/13/2026
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quick start

Installation and usage

Build enhancer-driven gene regulatory networks by integrating single-cell RNA-seq and ATAC-seq data using SCENIC+ to identify eRegulons linking transcription factors to enhancers and target genes. Use when analyzing 10x multiome or paired scRNA+scATAC data to infer cis-regulatory GRNs.

Installation
$ install --globalskills.sh
Usage

Once installed, you can use this skill by running the following command in your terminal:

skills use bio-gene-regulatory-networks-multiomics-grn