home/categories/framework-internals/mdbabumiamssm-llms-universal-life-science-and-clinical-skills-skills-genomics-genome-engineering-hdr-template-design-skill-md
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bio-genome-engineering-hdr-template-design
Design homology-directed repair donor templates for CRISPR knock-ins using primer3-py. Create ssODN, dsDNA, or plasmid templates with optimized homology arms. Use when designing donor templates for precise insertions, tagging, or allele replacement.
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mdbabumiamssm
Updated 2/4/2026
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quick start
Installation and usage
Design homology-directed repair donor templates for CRISPR knock-ins using primer3-py. Create ssODN, dsDNA, or plasmid templates with optimized homology arms. Use when designing donor templates for precise insertions, tagging, or allele replacement.
Installation
$ install --globalskills.sh
Usage
Once installed, you can use this skill by running the following command in your terminal:
skills use bio-genome-engineering-hdr-template-design