ubicaciones
Experto en geolocalización para SyV - validación de ubicaciones, coherencia espacial, cartografía de mundos post-apocalípticos y relaciones geográficas
Experto en geolocalización para SyV - validación de ubicaciones, coherencia espacial, cartografía de mundos post-apocalípticos y relaciones geográficas
Use when extracting entities and relationships, building ontologies, compressing large graphs, or analyzing knowledge structures - provides structural equivalence-based compression achieving 57-95% size reduction, k-bisimulation summarization, categorical quotient constructions, and metagraph hierarchical modeling with scale-invariant properties. Supports recursive refinement through graph topology metrics including |R|/|E| ratios and automorphism analysis.
Full de novo structure elucidation - skip dereplication and solve the structure from NMR correlations. Use when dereplication returned no matches, the compound is known to be novel, or you want to solve the structure from first principles.
Deep security analysis with high reasoning effort for threat detection
Teach Individual Patient Data (IPD) meta-analysis methods for analyzing raw participant-level data from multiple studies. Use when users have access to original datasets, need to explore treatment-effect modifiers, or want to conduct time-to-event analyses.
Teleological physiology analysis framework for understanding biological systems through multi-constraint optimization. Use when analyzing physiological mechanisms, explaining apparent biological "inefficiencies", preparing for medical examinations (CICM/ANZCA Primary), understanding why biological systems are designed the way they are, or when seeking deeper mechanistic understanding beyond descriptive knowledge. Triggers on questions like "why is X designed this way", "what purpose does Y serve", "how is Z optimized", analysis of physiological trade-offs, or exploration of evolutionary/design constraints.
CellCharter spatial transcriptomics analysis toolkit - complete documentation with precise file name-based categorization
Guidelines for rRNA detection and prediction including prokaryotic (16S, 23S, 5S) and eukaryotic (18S, 28S, 5.8S, 5S) ribosomal RNA. Covers sequence patterns, secondary structure, HMM models, blast-based detection, length validation, and quality scoring for rRNA identification.
Bayesian meta-analysis models including fixed effects, random effects, and network meta-analysis with Stan and JAGS implementations.
Monocle3 单细胞轨迹分析工具包 - 100%覆盖文档(18个文件:完整教程+API+轨迹推断)
Spectral similarity and compound identification for metabolomics. Use for comparing mass spectra, computing similarity scores (cosine, modified cosine), and identifying unknown compounds from spectral libraries. Best for metabolite identification, spectral matching, library searching. For full LC-MS/MS proteomics pipelines use pyopenms.
BANKSY spatial transcriptomics analysis tool - complete documentation with notebooks and source code
scvi-tools 单细胞深度学习框架 - 100%覆盖文档(完整API+教程+模型训练+多模态整合)
Comprehensive guide to phylogenetic tree visualization including matplotlib (Python), ggtree (R), and publication-quality figure generation. Covers rectangular, circular, radial layouts, bootstrap annotations, branch coloring, clade highlighting, and interactive visualizations. Based on best practices from Yulab's Tree Data Book.
Giotto Suite 空间转录组学分析工具包 - 100%覆盖718个文件(37个教程+285个核心API+4个数据文档+344个扩展函数+49个工具函数)
Run DEM lineament analysis to identify unmapped fault structures. Use when visually confirming orphan earthquake clusters, mapping fault extensions, or finding dark earthquake sources. Triggers on "DEM analysis", "lineament", "edge detection", "drainage analysis".
Resolves ambiguous organism names to precise NCBI taxonomy IDs and scientific names, then recommends appropriate IWC (Intergalactic Workflow Commission) Galaxy workflows for analysis. Use this skill when users provide common names (like "malaria parasite", "E. coli", "mouse"), abbreviated names, or when you need to convert any organism reference to an exact scientific name for API queries. This skill handles disambiguation through conversation, validates taxonomy IDs via NCBI Taxonomy API, provides ENA FASTQ search capabilities, and ALWAYS recommends existing IWC workflows rather than producing custom scripts or analysis steps.
Developing Heart Atlas - comprehensive cardiac development analysis with spatial multi-omics integration
scvi-tools 深度学习单细胞分析工具包 - 100%覆盖文档(321个文件:完整API+用户指南+教程+开发者文档)
Computer-Assisted Structure Elucidation (CASE) for organic natural products using NMR spectroscopy. Use when the user asks to identify an unknown compound from NMR data, perform structure elucidation, analyze HSQC/HMBC/DEPT/COSY spectra, run dereplication against natural product databases (COCONUT, NMRShiftDB), generate LSD solver input, rank candidate structures by 13C prediction, or determine molecular structure from Bruker NMR data. Requires molecular formula and Bruker-format NMR spectra.
SpatialData 空间组学数据框架 - 100%覆盖271个核心文件(API文档+教程+示例+核心概念)