Deep methodology knowledge for ML-NMR including IPD/AgD integration, population adjustment, numerical integration, and prediction to target populations. Use when conducting or reviewing ML-NMR analyses.

choxos

research

open

scientific-computing

bio-bam

This skill should be used when the user asks to analyze BAM/SAM/CRAM alignment files from WGS/WES sequencing. Triggers include requests to extract reads from specific regions, identify insertions and deletions, calculate coverage statistics, or export read data as JSON for downstream analysis.

dakesan

research

open

bioinformatics

group-sequential-methods

Group sequential design methods for interim analyses, alpha spending, and futility stopping. Use when designing trials with interim looks or implementing spending functions.

choxos

research

open

bioinformatics

multiplex-imaging-analysis

Optimizing segmentation feature extraction, SOM clustering, and spatial analysis for multiplex immunofluorescence imaging with cell compartment and ECM features

smith6jt-cop

research

open

bioinformatics

stan-coding

Best practices for writing efficient, clean Stan programs

sunxd3

research

open

bioinformatics

sfh-gen

Generate fractal horn geometries using space-filling curves and Mandelbrot expansion. Use when designing horn topology, creating geometry variations, or exploring fractal approaches for acoustic optimization. Produces STL meshes and fractal analysis data.

toneron2

research

open

bioinformatics

epsilon-yajna

Convert verbose memories to SSL v0.2 format - I am encoder AND decoder

genomewalker

research

open

bioinformatics

nma-methodology

Deep methodology knowledge for network meta-analysis including transitivity, consistency assessment, treatment rankings, and model selection. Use when conducting or reviewing NMA.

choxos

research

open

bioinformatics

face-alignment

Face alignment, landmark extraction, and quality gating. Use when debugging alignment issues, reviewing rejected faces, or tuning quality thresholds.

therealityreport

research

open

bioinformatics

scvelo-complete

scVelo RNA速度分析工具包 - 100%覆盖文档（78个文件：完整API+教程+动态建模+可视化）

Ketomihine

research

open

bioinformatics

scglue-complete

scGLUE 单细胞多组学数据整合工具包 - 100%覆盖文档（完整API+教程+数据整合+图谱分析）

Ketomihine

research

open

bioinformatics

phylogenetic-methods

Comprehensive guide to phylogenetic tree building methods including distance-based (UPGMA, Neighbor-Joining), maximum likelihood (RAxML, IQ-TREE), and Bayesian inference (MrBayes). Covers multiple sequence alignment, distance matrices, bootstrap analysis, consensus methods, tree formats (Newick, Nexus), and tree comparison metrics. Includes implementation patterns for tree visualization and evaluation.

roeimed0

research

open

bioinformatics

bio-blat

Runs local BLAT searches for DNA sequence alignment against hg38 or CHM13 using local .2bit references. Use when a user wants to align a DNA sequence without relying on UCSC API access.

dakesan

research

open

bioinformatics

balkan-family-tree

Comprehensive skill for working with Balkan Family Tree JS libraries (V1 and V2). Use when creating family tree visualizations, genealogy applications, org charts with family relationships, or when migrating between library versions. Covers initialization, data structures, templates, events, node manipulation, and V1→V2 migration patterns.