bioinformatics
687
genome-compare
Compare your genome to George Church (PGP-1) and estimate ancestry composition via IBS and EM admixture
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bioinformatics
687
clinical-variant-reporter
Classify germline variants from VCF/BCF files according to the ACMG/AMP 2015 28-criteria evidence framework and generate clinical-grade interpretation reports with per-variant evidence audit trails and ACMG SF v3.2 secondary findings screening.
ClawBio
research
bioinformatics
687
de-summary
Summarise pre-computed differential expression results with ranked gene lists, biological themes, and publication-ready interpretation.
ClawBio
research
bioinformatics
687
genome-match
Score genetic compatibility across all male-female pairings in a Genomebook generation
ClawBio
research
bioinformatics
687
claw-ancestry-pca
Ancestry decomposition PCA against the Simons Genome Diversity Project
ClawBio
research
bioinformatics
687
diff-visualizer
Rich downstream visualisation and reporting for bulk RNA-seq differential expression and scRNA marker/contrast outputs.
ClawBio
research
bioinformatics
687
struct-predictor
Protein structure prediction with Boltz-2. Accepts YAML inputs (single protein or multi-chain complex), runs boltz predict, extracts per-residue pLDDT and PAE confidence, and writes a markdown report with figures.
ClawBio
research
bioinformatics
687
gwas-lookup
Federated variant lookup across 9 genomic databases — GWAS Catalog, Open Targets, PheWeb (UKB, FinnGen, BBJ), GTEx, eQTL Catalogue, and more.
ClawBio
research
bioinformatics
687
claw-metagenomics
Shotgun metagenomics profiling — taxonomy, resistome, and functional pathways
ClawBio
research
bioinformatics
687
variant-annotation
Annotate VCF variants with Ensembl VEP REST, ClinVar significance, gnomAD/population frequency context, and prioritized variant ranking.
ClawBio
research
bioinformatics
687
vcf-annotator
Annotate VCF variants with VEP, ClinVar, gnomAD frequencies, and ancestry-aware context. Generates prioritised variant reports.
ClawBio
research
bioinformatics
687
scrna-embedding
Local scVI/scANVI-based single-cell latent embedding and batch-aware integration from raw-count .h5ad or 10x Matrix Market input, with stable integrated AnnData export for downstream latent analysis.
ClawBio
research
bioinformatics
687
scrna-orchestrator
Local Scanpy pipeline for single-cell RNA-seq QC, optional doublet detection, clustering, marker discovery, optional CellTypist annotation, optional latent downstream mode from integrated.h5ad/X_scvi, and optional dataset-level plus within-cluster contrastive marker analysis from raw-count .h5ad or 10x Matrix Market input.
ClawBio
research
bioinformatics
687
repro-enforcer
Export any bioinformatics analysis as a reproducible bundle with Conda environment, Singularity container definition, and Nextflow pipeline.
ClawBio
research
bioinformatics
687
pharmgx-reporter
Pharmacogenomic report from DTC genetic data (23andMe/AncestryDNA) — 12 genes, 31 SNPs, 51 drugs
ClawBio
research
bioinformatics
687
illumina-bridge
Import DRAGEN-exported Illumina result bundles into ClawBio for local tertiary analysis and downstream routing.
ClawBio
research
bioinformatics
687
nutrigx-advisor
Personalised nutrition report from consumer genetic data (23andMe, AncestryDNA, VCF) — interrogates nutritionally-relevant SNPs and generates actionable dietary guidance, all computed locally.
ClawBio
research
bioinformatics
687
methylation-clock
Compute epigenetic age from DNA methylation arrays using PyAging clocks from GEO accessions or local files.
ClawBio
research
computational-chemistry
687
clinical-trial-finder
Find clinical trials for a gene, variant, or condition from ClinicalTrials.gov + EUCTR, with FHIR R4 output
ClawBio
research
computational-chemistry
687
target-validation-scorer
Evidence-grounded target validation scoring with GO/NO-GO decisions for drug discovery campaigns
ClawBio
research
computational-chemistry
687
fine-mapping
Statistical fine-mapping of GWAS loci using SuSiE, SuSiE-inf, and Approximate Bayes Factors to identify credible sets and posterior inclusion probabilities (PIPs) for causal variant discovery. SuSiE-inf adds an infinitesimal polygenic component for improved calibration at well-powered loci.
ClawBio
research