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Science Comp.

Simulation and numerical analysis.

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scientific-computing
25

clinical-research-pitfalls

Avoid common methodological mistakes in clinical research with EHR databases. Covers immortal time bias, information leakage, selection bias, and other critical pitfalls.

hannesill
hannesill
research
open
scientific-computing
25

clinical-research-analysis-framework

Guided workflow for statistical and ML analysis of clinical data. Use when planning or executing research analyses on MIMIC, eICU, or similar EHR data. Ensures methodological rigor through structured consultation, assumption checking, and stepwise execution with audit trails.

hannesill
hannesill
research
open
scientific-computing
25

equiflow

Generate equity-focused cohort selection flow diagrams. Tracks demographic, socioeconomic, and outcome variables at each exclusion step and calculates SMD to detect selection bias. Use for cohort construction, CONSORT-style diagrams, or bias detection in clinical ML/research.

hannesill
hannesill
research
open
scientific-computing
25

signal-sciences

Signal Sciences integration. Manage data, records, and automate workflows. Use when the user wants to interact with Signal Sciences data.

membranedev
membranedev
research
open
scientific-computing
25

mimic-eicu-mapping

Map equivalent concepts between MIMIC-IV and eICU databases. Use for multi-database studies, external validation, or understanding structural differences between databases.

hannesill
hannesill
research
open
scientific-computing
25

particles-lifecycle

Particle lifecycle management—emission/spawning, death conditions, object pooling, trails, fade-in/out, and state transitions. Use when particles need birth/death cycles, continuous emission, trail effects, or memory-efficient recycling.

tanepiper
tanepiper
research
open
scientific-computing
24

research-analyst

Expert research analyst specializing in comprehensive information gathering, synthesis, and insight generation. Masters research methodologies, data analysis, and report creation with focus on delivering actionable intelligence that drives informed decision-making.

zenobi-us
zenobi-us
research
open
scientific-computing
24

claude-light

Expert assistant for conducting remote experiments with Claude-Light - a web-accessible RGB LED and spectral sensor instrument for statistics, regression, optimization, and design of experiments

jkitchin
jkitchin
research
open
scientific-computing
24

variant-interpretation-acmg

Classifies genetic variants according to ACMG (American College of Medical Genetics) guidelines.

mdbabumiamssm
mdbabumiamssm
research
open
scientific-computing
24

vasp

Expert assistant for VASP (Vienna Ab initio Simulation Package) calculations - input file generation, parameter selection, workflow setup, and best practices for accurate DFT calculations

jkitchin
jkitchin
research
open
scientific-computing
24

materials-properties

Expert assistant for calculating materials properties from first-principles using ASE - structure relaxation, surface energies, adsorption, reaction barriers, phonons, elastic constants, and thermodynamic modeling with proper scientific methodology

jkitchin
jkitchin
research
open
scientific-computing
24

materials-databases

Expert assistant for accessing materials databases (AFLOW and Materials Project) - query crystal structures, materials properties, thermodynamic data, and computational results from comprehensive databases

jkitchin
jkitchin
research
open
scientific-computing
24

design-of-experiments

Expert guidance for Design of Experiments (DOE) in Python - interactive goal-driven design selection, classical DOE (factorial, response surface, screening), Bayesian optimization with Gaussian processes, model-driven optimal designs, active learning, and sequential experimentation; includes pyDOE3, pycse, BoTorch, Ax, scikit-optimize, statsmodels

jkitchin
jkitchin
research
open
scientific-computing
24

adaptyv

Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.

oimiragieo
oimiragieo
research
open
scientific-computing
24

digital-twin-clinical-agent

AI-powered patient digital twin creation for clinical trial simulation, treatment outcome prediction, and personalized medicine using real-world data and multi-omics integration.

mdbabumiamssm
mdbabumiamssm
research
open
scientific-computing
24

neurokit2

Comprehensive biosignal processing toolkit for analyzing physiological data including ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use this skill when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements. Applicable for heart rate variability analysis, event-related potentials, complexity measures, autonomic nervous system assessment, psychophysiology research, and multi-modal physiological signal integration.

oimiragieo
oimiragieo
research
open
scientific-computing
24

exploratory-data-analysis

Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats. This skill should be used when analyzing any scientific data file to understand its structure, content, quality, and characteristics. Automatically detects file type and generates detailed markdown reports with format-specific analysis, quality metrics, and downstream analysis recommendations. Covers chemistry, bioinformatics, microscopy, spectroscopy, proteomics, metabolomics, and general scientific data formats.

oimiragieo
oimiragieo
research
open
scientific-computing
24

omero-integration

Microscopy data management platform. Access images via Python, retrieve datasets, analyze pixels, manage ROIs/annotations, batch processing, for high-content screening and microscopy workflows.

oimiragieo
oimiragieo
research
open
scientific-computing
24

scientific-skills

Comprehensive scientific research toolkit with 139 specialized skills for biology, chemistry, medicine, data science, and computational research. Transforms Claude into an AI research assistant with access to scientific databases, analysis tools, and domain-specific workflows.

oimiragieo
oimiragieo
research
open
scientific-computing
24

benchling-integration

Benchling R&D platform integration. Access registry (DNA, proteins), inventory, ELN entries, workflows via API, build Benchling Apps, query Data Warehouse, for lab data management automation.

oimiragieo
oimiragieo
research
open
scientific-computing
24

spatial-agent

An agent that interprets spatial transcriptomics data to propose mechanistic hypotheses and analyze tissue organization.

mdbabumiamssm
mdbabumiamssm
research
open
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