home/categories/lab-tools/freedomintelligence-openclaw-medical-skills-skills-bio-causal-genomics-pleiotropy-detection-skill-md
lab-toolsresearch

bio-causal-genomics-pleiotropy-detection

Detect and correct for horizontal pleiotropy in Mendelian randomization analyses using MR-PRESSO for outlier removal, MR-Egger regression for directional pleiotropy, and Steiger filtering for variant directionality. Use when validating MR results, detecting pleiotropic instruments, or running sensitivity analyses for causal inference.

FreedomIntelligence
maintainer
FreedomIntelligence
Atualizado 08/03/2026
Estrelas
1987
Forks
270
quick start

Installation and usage

Detect and correct for horizontal pleiotropy in Mendelian randomization analyses using MR-PRESSO for outlier removal, MR-Egger regression for directional pleiotropy, and Steiger filtering for variant directionality. Use when validating MR results, detecting pleiotropic instruments, or running sensitivity analyses for causal inference.

Instalação
$ install --globalskills.sh
Uso

Depois de instalar, você pode usar esta skill executando o seguinte comando no terminal:

skills use bio-causal-genomics-pleiotropy-detection