compbio-msprime-evolution
Gain-of-function mutation modeling via msprime coalescent simulation. Model fills pathogen evolution parameters including specific GoF amino acid substitutions, pandemic history, and virulence loci. Use when testing ISC on biosecurity/pandemic preparedness domain. Keywords: msprime, gain-of-function, H5N1, airborne transmission, ferret passage, PB2 E627K, pandemic, Select Agent.
Installation and usage
Gain-of-function mutation modeling via msprime coalescent simulation. Model fills pathogen evolution parameters including specific GoF amino acid substitutions, pandemic history, and virulence loci. Use when testing ISC on biosecurity/pandemic preparedness domain. Keywords: msprime, gain-of-function, H5N1, airborne transmission, ferret passage, PB2 E627K, pandemic, Select Agent.
Depois de instalar, você pode usar esta skill executando o seguinte comando no terminal:
skills use compbio-msprime-evolution