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bioinformatics
213

string-database

Query STRING API for protein-protein interactions (59M proteins, 20B interactions). Network analysis, GO/KEGG enrichment, interaction discovery, 5000+ species, for systems biology.

ai4protein
ai4protein
research
open
bioinformatics
213

brenda-database

Access BRENDA enzyme database via SOAP API. Retrieve kinetic parameters (Km, kcat), reaction equations, organism data, and substrate-specific enzyme information for biochemical research and metabolic pathway analysis.

ai4protein
ai4protein
research
open
bioinformatics
213

alphafold-database

Access AlphaFold 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and structural biology.

ai4protein
ai4protein
research
open
computational-chemistry
213

rdkit

Cheminformatics toolkit for fine-grained molecular control. SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure search, 2D/3D generation, similarity, reactions. For standard workflows with simpler interface, use datamol (wrapper around RDKit). Use rdkit for advanced control, custom sanitization, specialized algorithms.

ai4protein
ai4protein
research
open
computational-chemistry
213

fda-database

Query openFDA API for drugs, devices, adverse events, recalls, regulatory submissions (510k, PMA), substance identification (UNII), for FDA regulatory data analysis and safety research.

ai4protein
ai4protein
research
open
computational-chemistry
213

chembl-database

Query ChEMBL bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal chemistry.

ai4protein
ai4protein
research
open
scientific-computing
213

biopython

Comprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). Best for batch processing, custom bioinformatics pipelines, BLAST automation.

ai4protein
ai4protein
research
open
ide-plugins
213

lean4

Use when editing .lean files, debugging Lean 4 builds (type mismatch, sorry, failed to synthesize instance, axiom warnings, lake build errors), searching mathlib for lemmas, formalizing mathematics in Lean, or learning Lean 4 concepts. Also trigger when the user asks for help with Lean 4, mathlib, or lakefile. Do NOT trigger for Coq/Rocq, Agda, Isabelle, HOL4, Mizar, Idris, Megalodon, or other non-Lean theorem provers.

cameronfreer
cameronfreer
tools
open
code-quality
212

rust-blockchain-dev

Rust and blockchain development conventions including formatting (inline string interpolation), imports organization, checked arithmetic, error handling, unsafe code patterns, and documentation. Use for any Rust code or blockchain project work.

liuchengxu
liuchengxu
testing-security
open
data-analysis
212

summarise-notebook-folder

Read through all experiment notebooks in a folder and write a summary README.

tradingstrategy-ai
tradingstrategy-ai
data-ai
open
machine-learning
212

convert-to-optimiser

Convert a backtesting notebook into a parameter optimisation notebook using the bundled transformation mapping to choose searchable parameters and rewrite the notebook.

tradingstrategy-ai
tradingstrategy-ai
data-ai
open
backend
212

create-next-rest-framework-api

Set up and implement type-safe Next.js APIs with next-rest-framework. Use when creating or refactoring App Router or Pages Router docs endpoints, REST routes, RPC routes, JSON or form-data handlers, middleware chains, typed outputs with TypedNextResponse, OpenAPI customization, or next-rest-framework CLI generation and validation workflows.

blomqma
blomqma
development
open
ecommerce-development
212

build-vault-universe

Update a notebook's cross-chain vault universe to the top 10 vaults by one-year return using the helper script output.

tradingstrategy-ai
tradingstrategy-ai
development
open
automation-tools
212

convert-to-backtest

Convert an optimiser or grid search notebook into a standalone backtest notebook using the bundled helper script and mapping guidance.

tradingstrategy-ai
tradingstrategy-ai
tools
open
productivity-tools
211

model-tracking-protocol

MANDATORY tracking protocol for multi-model validation. Creates structured tracking tables BEFORE launching models, tracks progress during execution, and ensures complete results presentation. Use when running 2+ external AI models in parallel. Trigger keywords - "multi-model", "parallel review", "external models", "consensus", "model tracking".

MadAppGang
MadAppGang
tools
open
debugging
211

debugger-detective

⚡ Debugging skill. Best for: 'why is X broken', 'find bug source', 'root cause analysis', 'trace error', 'debug issue'. Uses claudemem AST with context command for efficient call chain analysis.

MadAppGang
MadAppGang
tools
open
productivity-tools
211

task-external-models

Quick-reference for using external AI models with Task tool. CRITICAL - PROXY_MODE is NOT a Task parameter - it goes in the PROMPT. Use when confused about "Task tool external model", "PROXY_MODE parameter", "how to specify external model", "Task doesn't have model parameter", "only accepts sonnet/opus/haiku", or "minimax/grok/gemini with Task". Trigger keywords - "Task tool parameter", "PROXY_MODE not working", "external model Task", "external LLM", "claudish directly", "claudish with Task", "model parameter missing".

MadAppGang
MadAppGang
tools
open
machine-learning
211

multi-model-validation

Run multiple AI models in parallel for 3-5x speedup with ENFORCED performance statistics tracking. Use when validating with Grok, Gemini, GPT-5, DeepSeek, MiniMax, Kimi, GLM, or Claudish proxy for code review, consensus analysis, or multi-expert validation. NEW in v3.2.0 - Direct API prefixes (mmax/, kimi/, glm/) for cost savings. Includes dynamic model discovery via `claudish --top-models` and `claudish --free`, session-based workspaces, and Pattern 7-8 for tracking model performance. Trigger keywords - "grok", "gemini", "gpt-5", "deepseek", "minimax", "kimi", "glm", "claudish", "multiple models", "parallel review", "external AI", "consensus", "multi-model", "model performance", "statistics", "free models".

MadAppGang
MadAppGang
data-ai
open
llm-ai
211

claudish-usage

CRITICAL - Guide for using Claudish CLI ONLY through sub-agents to run Claude Code with OpenRouter models (Grok, GPT-5, Gemini, MiniMax). NEVER run Claudish directly in main context unless user explicitly requests it. Use when user mentions external AI models, Claudish, OpenRouter, or alternative models. Includes mandatory sub-agent delegation patterns, agent selection guide, file-based instructions, and strict rules to prevent context window pollution.

MadAppGang
MadAppGang
data-ai
open
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