Comprehensive spreadsheet creation, editing, and analysis with support for formulas, formatting, data analysis, and visualization. When Claude needs to work with spreadsheets (.xlsx, .xlsm, .csv, .tsv, etc) for: (1) Creating new spreadsheets with formulas and formatting, (2) Reading or analyzing data, (3) Modify existing spreadsheets while preserving formulas, (4) Data analysis and visualization in spreadsheets, or (5) Recalculating formulas
CHARLS (China Health and Retirement Longitudinal Study) database-specific knowledge for reproducing published papers. Use when reproducing or analyzing papers that use CHARLS data, including variable mapping from harmonized to raw questionnaire items, cognitive function scoring (episodic memory, mental status, TICS), CESD-10 depression screening, social isolation index construction, and chronic disease coding. Also use for any CHARLS data cleaning, variable construction, or cohort selection task.
Grid-based geographic clustering with O(n) performance, medoid finding for map markers, and multi-factor risk scoring from event density, sentiment, and recency.
Covers publication-ready matplotlib figures for academic papers, slides, and reports—bars, trends, scatter, heatmaps, and multi-panel layouts—with this repository’s house style, print/vector export conventions, and parity with figures4papers demos. Use when the user is finalizing or creating such figures in matplotlib. Do not use for interactive dashboards or web viz (Plotly, Altair, Bokeh), exploratory-only plots without a publication target, dominant 3D or geographic mapping, or Illustrator/Figma-first infographic workflows.
Submit compact eQTL Catalogue API requests for association retrieval and documented metadata endpoints. Use when a user wants concise public eQTL Catalogue summaries
Submit compact ClinicalTrials.gov API v2 requests for study search, metadata, enums, search areas, and field statistics. Use when a user wants concise ClinicalTrials.gov summaries
Submit compact Open Targets Platform GraphQL requests for target, disease, drug, variant, study, and search data, including associated-disease datasource heatmap matrices. Use when a user wants concise Open Targets summaries or per-datasource evidence context
Fetch compact TPMI PheWAS summaries for single variants by accepting rsID, GRCh37, or GRCh38 input and resolving to the required GRCh38 query. Use when a user wants concise TPMI association results for one variant
Submit compact GWAS Catalog REST API v2 requests for studies, associations, SNPs, EFO traits, genes, publications, loci, and metadata. Use when a user wants concise GWAS Catalog summaries
Submit compact HMDB search requests for metabolites, proteins, diseases, and pathways. Use when a user wants concise HMDB summaries
Submit compact MGnify API requests for microbiome studies, samples, and biome metadata. Use when a user wants concise MGnify summaries
Submit compact MetaboLights requests for study discovery and study-level metabolomics metadata. Use when a user wants concise MetaboLights summaries
Aggregate and rank signals from multiple edge-finding skills (edge-candidate-agent, theme-detector, sector-analyst, institutional-flow-tracker) into a prioritized conviction dashboard with weighted scoring, deduplication, and contradiction detection.
Analyze historical downtrend durations and generate interactive HTML histograms showing typical correction lengths by sector and market cap.
Write and debug spreadsheet formulas (Excel/Google Sheets), pivot tables, and array formulas; translate between dialects; use when users need working formulas with examples and edge-case checks.
Data analysis and interpretation — tabular data, trend identification, statistical summaries, comparisons, chart recommendations, anomaly detection.
Recommend and generate appropriate data visualizations using GPT-Vis syntax. Supports 25 chart types including statistical charts (line, column, bar, pie, area, scatter, dual-axes, histogram, boxplot, radar, funnel, waterfall, liquid, word-cloud, violin, venn, treemap), flow charts (sankey, flow-diagram), relation charts (mindmap, indented-tree, network-graph, organization-chart), and data display (table, summary). Provides workflow from intent recognition to chart selection, syntax generation, and code generation for HTML, React, or Vue.
Aggregate public target-level evidence across omics and translational sources for research triage.
Compute HEIM diversity and equity metrics from VCF or ancestry data. Generates heterozygosity, FST, PCA plots, and a composite HEIM Equity Score with markdown reports.
Extract numerical data from scientific figure images using Claude vision + OpenCV calibration. Supports 26+ plot types including bar charts, scatter plots, forest plots, Kaplan-Meier curves, box plots, and more.
Deterministic mathematical computation using SymPy. Use for ANY math operation requiring exact/verified results - basic arithmetic, algebra (simplify, expand, factor, solve equations), calculus (derivatives, integrals, limits, series), linear algebra (matrices, determinants, eigenvalues), trigonometry, number theory (primes, GCD/LCM, factorization), and statistics. Ensures mathematical accuracy by using symbolic computation rather than LLM estimation.
Comprehensive data analysis skill for CSV files using Python and pandas
Best practices for creating research diagrams with Excalidraw MCP tools
