Performs quality control on single-cell RNA-seq data (.h5ad or .h5 files) using scverse best practices with MAD-based filtering and comprehensive visualizations. Use when users request QC analysis, filtering low-quality cells, assessing data quality, or following scverse/scanpy best practices for single-cell analysis.
Multi-source research on a customer question or topic with source attribution. Use when a customer asks something you need to look up, investigating whether a bug has been reported before, checking what was previously told to a specific account, or gathering background before drafting a response.
Combines search results from multiple sources into coherent, deduplicated answers with source attribution. Handles confidence scoring based on freshness and authority, and summarizes large result sets effectively.
Query decomposition and multi-source search orchestration. Breaks natural language questions into targeted searches per source, translates queries into source-specific syntax, ranks results by relevance, and handles ambiguity and fallback strategies.
Research a company or person and get actionable sales intel. Works standalone with web search, supercharged when you connect enrichment tools or your CRM. Trigger with "research [company]", "look up [person]", "intel on [prospect]", "who is [name] at [company]", or "tell me about [company]".
Run nf-core bioinformatics pipelines (rnaseq, sarek, atacseq) on sequencing data. Use when analyzing RNA-seq, WGS/WES, or ATAC-seq data—either local FASTQs or public datasets from GEO/SRA. Triggers on nf-core, Nextflow, FASTQ analysis, variant calling, gene expression, differential expression, GEO reanalysis, GSE/GSM/SRR accessions, or samplesheet creation.
Support SOX 404 compliance with control testing methodology, sample selection, and documentation standards. Use when generating testing workpapers, selecting audit samples, classifying control deficiencies, or preparing for internal or external audits.
This skill should be used when the user wants to analyze hermesvm binary size changes across a range of commits. Use when the user mentions "binary size", "size analysis", "size regression", "size increase", or asks to measure how commits affect the hermesvm library size.
Systematic literature review methodology including search strategy, screening, and synthesis. Use when conducting literature reviews or writing background sections.
Academic manuscript writing with IMRAD structure, citation formatting, and reporting guidelines. Use when drafting or revising research papers.
Statistical test selection, assumption checking, and APA-formatted reporting. Use when analyzing experimental results or writing results sections.
Structured methodology for comprehensive literature review following PRISMA guidelines. Use during literature search and screening stages.
Best practices for image classification tasks. Use when working on CIFAR, ImageNet, or other classification benchmarks.
Bioinformatics with Biopython for sequence manipulation, file parsing, BLAST, and phylogenetics. Use when working with DNA/RNA/protein sequences or biological databases.
Computational chemistry with RDKit for molecular analysis, descriptors, fingerprints, and substructure search. Use when working with SMILES, drug discovery, or cheminformatics tasks.
Best practices for object detection tasks. Use when working on COCO, VOC, or detection architectures like YOLO and DETR.
Best practices for designing reproducible ML experiments. Use when planning ablations, baselines, or controlled experiments.
Research topics on the web, gather information from multiple sources, and summarize findings.
Use when the user asks to review pull requests, analyze code changes, check for security issues in PRs, or assess code quality of diffs.
FDA regulatory consultant for medical device companies. Provides 510(k)/PMA/De Novo pathway guidance, QSR (21 CFR 820) compliance, HIPAA assessments, and device cybersecurity. Use when user mentions FDA submission, 510(k), PMA, De Novo, QSR, premarket, predicate device, substantial equivalence, HIPAA medical device, or FDA cybersecurity.
