Guidance for finding probability distributions that satisfy specific statistical constraints such as KL divergence targets, entropy requirements, or moment conditions. This skill should be used when tasks involve constructing discrete or continuous probability distributions with specified divergence measures, entropy values, or other distributional properties through numerical optimization.
Search bioRxiv biology preprints with natural language queries. Semantic search powered by Valyu.
Search ChEMBL bioactive molecules database with natural language queries. Find compounds and assay data with Valyu semantic search.
Defensive exploratory data analysis for scientific data (CSV, FASTA, etc.). Context-first, human-guided; one plot at a time, ask why before executing, append-only journal per session, scripts with PEP723 and uv run, WebP plots. Use when opening data files for EDA or when the user wants guided scientific data exploration.
Conduct machine learning experiments from planning through evaluation and report writing. Use when running ML experiments, testing hypotheses, training models, or writing up results. Covers single-hypothesis scoping, fast iteration loops, targeted logging, JOURNAL.md protocol, data-backed diagnostic plots, and scientific report writing.
Guide when to use built-in tools (WebFetch, WebSearch) and MCP servers (Parallel Search, Perplexity, Context7) for research. Synthesize findings into narrative for braindump. Use when gathering data, examples, or citations for blog posts.
Parse, navigate, and query materials science ontology structures — browse class hierarchies, inspect individual classes and their properties, look up object and data property definitions with domain/range, search for ontology terms by keyword, and parse or summarize raw OWL/XML files. Supports the OCDO ecosystem (CMSO, ASMO, CDCO, PODO, PLDO, LDO). Use when exploring what classes or properties an ontology provides, finding the right CMSO term for a crystal structure or simulation concept, understanding parent-child class relationships, or onboarding to an unfamiliar materials ontology, even if the user only says "what ontology terms describe my FCC copper simulation" or "show me the CMSO class hierarchy."
Build, review, debug, and automate GROMACS molecular simulation workflows. Use when working with GROMACS preprocessing, topology and coordinate files, `.mdp` parameters, energy minimization, equilibration, production MD, analysis commands, or GROMACS runtime errors.
Generate, review, debug, and recover LAMMPS molecular dynamics input scripts. Use when working with LAMMPS command ordering, data files, force fields, ensembles, neighbor settings, thermo output, or common runtime errors such as lost atoms and non-numeric pressure.
Build, review, debug, and automate ElmerFEM workflows. Use when working with Elmer `.sif` solver input files, mesh directories, equation and material blocks, multiphysics coupling, boundary conditions, transient controls, or ElmerSolver execution and output issues.
Build, review, debug, and automate Gaussian quantum chemistry workflows. Use when working with Gaussian input files, Link 0 directives, route sections, charge and multiplicity, basis sets, SCF or optimization or frequency jobs, checkpoint handoff, or Gaussian execution and restart issues.
Systematic technology and market reconnaissance for extracting actionable intelligence from repositories, papers, and competitive landscapes.
TAM/SAM/SOM calculation, competitor analysis, and market trends identification. Use when analyzing markets, validating business ideas, or entering new markets.
Analyzes your 23andMe genetic data to identify health risks, drug sensitivities, ancestry, and traits, then generates a personalized report
Use Zo to research any topic comprehensively and write a report.
Identify EMERGING trends by connecting dots across unrelated sources. Monitor niche communities, academic research, GitHub, patents, funding, regulatory changes. Predict what will trend in 3-6 months based on weak signals.
CoreML diagnostics - model load failures, slow inference, memory issues, compression accuracy loss, compute unit problems, conversion errors.
Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology. Requires authentication.
Comprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). Best for batch processing, custom bioinformatics pipelines, BLAST automation. For quick lookups use gget; for multi-service integration use bioservices.
Finds duplicate or near-duplicate images in FiftyOne datasets using brain similarity computation. Use when deduplicating datasets, finding similar images, or removing redundant samples.
Transform, manipulate, and analyze JSON data structures with advanced operations.
