Use when the user asks to prepare, cut, validate, tag, or publish a ClawBox desktop release. Covers the UTC date-based version flow (`npm run release:version`), release validation commands, release commit/tag creation, and pushing the matching `v` tag for the current package version that triggers GitHub Releases. Do not use for changing packaging or versioning logic itself; use the packaging skill for that.
One-time setup of supply-chain protections for a project. Detects the package manager (npm, pnpm, Yarn, Bun), installs Socket Firewall (sfw), configures a 48-hour minimum package release age, and writes persistent dependency rules to CLAUDE.md. Use when the user mentions supply chain protection, dependency security, securing packages, malicious dependencies, typosquatting defense, "setup sfw", Socket Firewall, package release age, or wants to harden their project against compromised npm/pnpm/yarn/bun packages — even if they don't use these exact terms.
Interactive setup for the dev-tooling plugin (PHPStan, ECS, PHPUnit, ESLint, Stylelint, Jest MCP servers). Creates .mcp-php-tooling.json and optionally .mcp-js-tooling.json with the correct execution environment (native, docker, vagrant, ddev). Checks that jq is installed. Use when the user installs dev-tooling and needs configuration, asks how to set up PHP or JS tooling, or when php-tooling/js-tooling MCP tools fail with missing config errors.
Use when comparing modified OxCaml packages against pristine upstream, finding package sources, or understanding what changes were made to a vendored package
Cluster TCR/BCR clones by CDR3 sequences using GIANA or ClusTCR (both Faiss-based). Adds `CDR3_Cluster` column to metadata for clonotype analysis.
Progressive-disclosure workflow for ANDES studies. Use when the user asks to run ANDES through PowerMCP for power flow, small-signal stability, or time-domain simulation, and when the agent should expose base-case steps before advanced dynamic analysis.
Master skill for generating immunopipe pipeline configurations. Determines pipeline architecture based on data type (scRNA-seq with or without scTCR/BCR-seq) and analysis requirements. Routes to individual process skills for detailed configuration. Use this skill when starting a new immunopipe configuration or modifying pipeline-level options.
对蛋白pdb文件，进行预处理，对N、C端进行封端，对特定残基进行离子化，弥补缺失的原子等。得到准备好的pdb文件
Query and download public cancer imaging data from NCI Imaging Data Commons using idc-index. Use for accessing large-scale radiology (CT, MR, PET) and pathology datasets for AI training or research. No authentication required. Query by metadata, visualize in browser, check licenses.
Progressive-disclosure workflow for OpenDSS feeder studies. Use when the user asks to compile a DSS model, solve a distribution circuit, inspect feeder voltages or power, run load multipliers, or perform daily or harmonic studies through PowerMCP, with base-case checks before advanced scenarios.
This skill is used to perform de novo molecule generation basd on a given protein and a coordinate of center of pocket.
模拟计算液相的热传导系数(thermal conductivity)，多分子堆积成液相盒子，在NPT系综下进行分子动力学（molecule dynamics, MD)计算。分子输入的格式可以是.sdf, .mol, .csv以及smiles等多种格式
模拟计算液相的压缩系数(isothermal compressibility)，多分子堆积成液相盒子，在NPT系综下进行分子动力学（molecule dynamics, MD)计算。分子输入的格式可以是.sdf, .mol, .csv以及smiles等多种格式
模拟计算液相的热膨胀系数(coefficient of thermal expansion)，多分子堆积成液相盒子，在NPT系综下进行分子动力学（molecule dynamics, MD)计算。分子输入的格式可以是.sdf, .mol, .csv以及smiles等多种格式
