Cross-Species Comparative Genomics - Compare genomes across species: Ensembl compara, alignment, gene trees, and NCBI taxonomy. Use this skill for comparative genomics tasks involving get info compara species sets get alignment region get genetree member symbol get taxonomy. Combines 4 tools from 2 SCP server(s).
Protein Similarity Search - Search for similar proteins: extract sequence from PDB, search structures with FoldSeek, find homologs with STRING, and check UniProt. Use this skill for bioinformatics tasks involving extract pdb sequence foldseek search get best similarity hits between species search uniprotkb entries. Combines 4 tools from 3 SCP server(s).
Generate new peptide molecules sampling from the input peptide sequence.
Generate new molecules sampling from the input scaffold.
Multi-Omics Integration - Integrate multi-omics: gene expression, protein data, pathway enrichment, and metabolic pathways. Use this skill for multi-omics tasks involving get gene expression across cancers get uniprotkb entry by accession get functional enrichment kegg get. Combines 4 tools from 4 SCP server(s).
Nuclear Physics Calculations - Nuclear physics: energy conversion MeV to J, calculate total power, photon rate, and error analysis. Use this skill for nuclear physics tasks involving convert energy MeV to J calculate total power calculate incident photon rate calculate absolute error. Combines 4 tools from 3 SCP server(s).
Energy Unit Conversion Pipeline - Convert between energy units and analyze: MeV to Joules, scientific notation, and error calculation. Use this skill for physics tasks involving convert energy MeV to J convert to scientific notation format scientific notation calculate absolute error. Combines 4 tools from 2 SCP server(s).
Mouse Model Disease Analysis - Analyze mouse disease models: MouseMine search, NCBI mouse gene data, Ensembl cross-species comparison, and orthologs. Use this skill for model organisms tasks involving mousemine search get gene metadata by gene name get homology symbol get gene orthologs. Combines 4 tools from 3 SCP server(s).
Mutation Impact Analysis - Analyze mutation impact: predict structure, predict mutations from sequence and structure, and check variant effects with Ensembl VEP. Use this skill for molecular biology tasks involving pred protein structure esmfold zero shot sequence prediction predict zero shot structure get vep hgvs. Combines 4 tools from 3 SCP server(s).
Virus Genomics Analysis - Analyze virus genomics: NCBI virus dataset, annotation, taxonomy, and literature search. Use this skill for virology tasks involving get virus dataset report get virus annotation report get taxonomy search literature. Combines 4 tools from 2 SCP server(s).
Convert physical quantities and units at nanoscale for materials science and nanotechnology applications.
Retrieve protein sequences and functional information from UniProt database by protein name, enabling protein analysis and bioinformatics workflows.
Calculate basic molecular properties from SMILES including molecular weight, formula, atom counts, and exact mass.
Organism Classification & Database - Classify organism: NCBI taxonomy, Ensembl taxonomy, ChEMBL organisms, and genome info. Use this skill for taxonomy tasks involving get taxonomy get taxonomy id get organism by id get genome dataset report by taxon. Combines 4 tools from 3 SCP server(s).
Research technical solutions by searching the web, examining GitHub repos, and gathering evidence. Use when exploring implementation options or evaluating technologies.
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation reports (evidence-based guidelines with decision algorithms). Supports GRADE evidence grading, statistical analysis (hazard ratios, survival curves, waterfall plots), biomarker integration, and regulatory compliance. Outputs publication-ready LaTeX/PDF format optimized for drug development, clinical research, and evidence synthesis.
Use this skill when working with scientific research tools and workflows across bioinformatics, cheminformatics, genomics, structural biology, proteomics, and drug discovery. This skill provides access to 600+ scientific tools including machine learning models, datasets, APIs, and analysis packages. Use when searching for scientific tools, executing computational biology workflows, composing multi-step research pipelines, accessing databases like OpenTargets/PubChem/UniProt/PDB/ChEMBL, performing tool discovery for research tasks, or integrating scientific computational resources into LLM workflows.
This skill should be used when analyzing business sales and revenue data from CSV files to identify weak areas, generate statistical insights, and provide strategic improvement recommendations. Use when the user requests a business performance report, asks to analyze sales data, wants to identify areas of weakness, or needs recommendations on business improvement strategies.
Progressive L1-L6 refactoring hierarchy, 22 code smell taxonomy, atomic transformations, test code smells, and Fowler refactoring catalog
Generate publication-quality molecular visualization images using PyMOL. Use this skill whenever the user mentions PyMOL, molecular visualization, protein rendering, structure figures, PDB visualization, ray tracing molecules, or wants to create images of proteins, ligands, binding sites, protein-protein interactions, or any biomolecular structure. Also trigger when the user wants to: make a figure of a crystal structure for a paper or presentation; render a protein surface; show binding pockets; visualize protein-ligand interactions; create Goodsell-style illustrations; produce cartoon representations with highlighted residues; compare multiple structures side by side; or generate any molecular graphics output — even if they don't mention "PyMOL" by name. Trigger for any request involving PDB files, molecular surfaces, cartoon ribbons, stick models, electron density, or structural biology figures.
Remotion spring physics for motion graphics video production. Bouncy entrances, elastic trails, orchestrated sequences, physics presets, and organic motion patterns that interpolate() alone cannot achieve.
Mass spectrometry proteomics QC, quantification, comparative analysis, and export for DDA, DIA, and protein-level result tables.
